{"id":49840,"date":"2018-10-11T00:00:00","date_gmt":"2018-10-11T00:00:00","guid":{"rendered":"https:\/\/www.cpr.cuhk.edu.hk\/press\/cuhk-fruitencode-project-finds-the-hidden-treasures-in-junk-dna-in-eleventh-fleshy-fruit-genomes-paving-the-way-to-healthier-fruits\/"},"modified":"2018-10-11T00:00:00","modified_gmt":"2018-10-11T00:00:00","slug":"cuhk-fruitencode-project-finds-the-hidden-treasures-in-junk-dna-in-eleventh-fleshy-fruit-genomes-paving-the-way-to-healthier-fruits","status":"publish","type":"press","link":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/press\/cuhk-fruitencode-project-finds-the-hidden-treasures-in-junk-dna-in-eleventh-fleshy-fruit-genomes-paving-the-way-to-healthier-fruits\/","title":{"rendered":"\u4e2d\u5927fruitENCODE\u9805\u76ee\u5f9e11\u7a2e\u8089\u8cea\u679c\u5be6\u7684\u300c\u5783\u573eDNA\u300d\u627e\u51fa\u96b1\u85cf\u7470\u5bf6\u70ba\u57f9\u690d\u66f4\u5065\u5eb7\u6c34\u679c\u958b\u5275\u65b0\u65b9\u5411"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","tags":[],"class_list":["post-49840","press","type-press","status-publish","hentry"],"acf":{"title_alt":"","sub_title_alt":"","press_date":"20181011","keep":false,"details":"<p>\u9999\u6e2f\u4e2d\u6587\u5927\u5b78 (\u4e2d\u5927) \u751f\u547d\u79d1\u5b78\u5b78\u9662\u52a9\u7406\u6559\u6388\u937e\u601d\u6797\u6559\u6388\u7387\u9818\u4e00\u652f\u96f2\u96c6\u4f86\u81ea\u7f8e\u570b\u3001\u82f1\u570b\u3001\u897f\u73ed\u7259\u548c\u963f\u6839\u5ef7\u690d\u7269\u5b78\u5bb6\u7684\u570b\u969b\u5718\u968a\uff0c\u6700\u8fd1\u95e1\u660e\u4e86\u8089\u8cea\u679c\u5be6\u9032\u5316\u7684\u907a\u50b3\u548c\u8868\u89c0\u907a\u50b3\u57fa\u790e\uff0c\u6709\u52a9\u65e5\u5f8c\u57f9\u690d\u542b\u6709\u66f4\u9ad8\u71df\u990a\u50f9\u503c\u7684\u6c34\u679c\u3002\u9019\u9805\u7814\u7a76\u7d50\u679c\u5df2\u65bc\u8457\u540d\u79d1\u5b78\u671f\u520a<em>\u300a<\/em><em>Nature Plants<\/em><em>\u300b<\/em>\u767c\u8868\u3002&nbsp;<\/p><p>\u8089\u8cea\u679c\u5be6\u542b\u6709\u8c50\u5bcc\u7684\u7e96\u7dad\u3001\u7dad\u751f\u7d20\u3001\u7926\u7269\u8cea\u3001\u690d\u7269\u5316\u5b78\u7269\u8cea\u548c\u6297\u6c27\u5316\u5291\uff0c\u9032\u98df\u5b83\u5011\u5728\u4eba\u985e\u5065\u5eb7\u98f2\u98df\u4e2d\u8d77\u91cd\u8981\u4f5c\u7528\u3002\u5c0d\u690d\u7269\u800c\u8a00\uff0c\u679c\u5be6\u662f\u7531\u82b1\u6735\u6f14\u8b8a\u800c\u4f86\u4e26\u651c\u5e36\u7a2e\u5b50\u7684\u69cb\u9020\u3002\u53e4\u8001\u7684\u958b\u82b1\u690d\u7269\u7d50\u51fa\u7684\u4e7e\u679c\u5be6\uff0c\u53ef\u4ee5\u900f\u904e\u98a8\u529b\u50b3\u64ad\u3001\u6a5f\u68b0\u6563\u64ad\u6216\u4f9d\u9644\u5728\u52d5\u7269\u7684\u6bdb\u76ae\u4e0a\u50b3\u64ad\u3002\u8089\u8cea\u679c\u5be6\u65bc\u5927\u7d04\u516b\u5343\u842c\u5e74\u524d\u624d\u9032\u5316\u81f3\u4f7f\u690d\u7269\u80fd\u5920\u8207\u98df\u7528\u679c\u5be6\u7684\u52d5\u7269\u8d77\u76f8\u4e92\u4f5c\u7528\uff0c\u4e26\u900f\u904e\u52d5\u7269\u6392\u4fbf\u628a\u7a2e\u5b50\u5206\u6563\u5230\u9060\u8655\uff0c\u5927\u5927\u63d0\u9ad8\u7e41\u6b96\u7684\u6210\u529f\u7387\u3002&nbsp;<\/p><p>\u5118\u7ba1\u8a31\u591a\u8089\u8cea\u679c\u5be6\u57fa\u56e0\u7d44\u5df2\u88ab\u6e2c\u5e8f\uff0c\u79d1\u5b78\u5bb6\u4ecd\u4e0d\u77e5\u9053\u690d\u7269\u5982\u4f55\u80fd\u9032\u5316\u51fa\u5982\u6b64\u591a\u6a23\u5316\u7684\u679c\u5be6\u3002\u4e00\u500b\u91cd\u8981\u7684\u5553\u793a\u662f\u4e0d\u540c\u679c\u5be6\u6240\u9700\u7684\u57fa\u56e0\u65e9\u5df2\u5b58\u5728\u65bc\u53e4\u8001\u7684\u958b\u82b1\u690d\u7269\u57fa\u56e0\u7d44\u4e2d\uff1b\u56e0\u6b64\u7b54\u6848\u4e26\u975e\u5728\u86cb\u767d\u7de8\u78bc\u57fa\u56e0\u5167\uff0c\u800c\u662f\u5b58\u5728\u65bc\u975e\u86cb\u767d\u7de8\u78bc\u5340\u57df\u5167\u3001\u4ee5\u5f80\u88ab\u8a8d\u70ba\u662f\u7121\u7528\u7684\u300c\u5783\u573eDNA\u300d\u3002&nbsp;<\/p><p>\u7531\u4e2d\u5927\u9818\u5c0e\u4e26\u7372\u5168\u7403\u690d\u7269\u5b78\u5bb6\u652f\u6301\u7684<strong>fruitENCODE<\/strong>\u806f\u76df\uff0c\u4fc3\u6210\u4e86\u4e00\u500b\u8f09\u670911\u7a2e\u8089\u8cea\u679c\u5be6\u7684\u5168\u9762\u529f\u80fd\u57fa\u56e0\u7d44\u6578\u64da\u5eab\uff0c\u5305\u62ec361\u7d44\u57fa\u56e0\u8868\u9054\u8cc7\u6599\u300171\u7d44\u5168\u57fa\u56e0\u7d44\u958b\u653e\u67d3\u8272\u8cea\u5340\u57df\u5716\u8b5c\u3001147\u7d44\u7d44\u86cb\u767d\u4fee\u98fe\u8cc7\u6599\u53ca45\u7d44\u5168\u57fa\u56e0\u7d44DNA\u7532\u57fa\u5316\u5716\u8b5c\u3002\u901a\u904e\u6bd4\u8f03\u9019\u4e9b\u679c\u5be6\u57fa\u56e0\u7d44\u4e2d\u7684\u975e\u7de8\u78bc\u8abf\u63a7\u5143\u7d20\uff0c\u7814\u7a76\u4eba\u54e1\u767c\u73fe\u4e86\u4e09\u7a2e\u8abf\u7bc0\u8089\u8cea\u679c\u5be6\u6210\u719f\u9032\u5316\u7684\u8def\u5f91\u3002\u96d9\u5b50\u8449\u679c\u5be6\u4e2d\u7684\u860b\u679c\u3001\u68a8\u548c\u8543\u8304\u662f\u7531\u8907\u88fd\u958b\u82b1\u7684\u57fa\u56e0\u9032\u5316\uff0c\u4ee5\u63a7\u88fd\u679c\u5be6\u7684\u6210\u719f\uff1b\u871c\u74dc\u3001\u6843\u548c\u6728\u74dc\u5247\u4f7f\u7528\u63a7\u88fd\u8870\u8001\u7684\u57fa\u56e0\u3002\u55ae\u5b50\u8449\u690d\u7269\u9999\u8549\u5728\u5927\u7d041\u5104\u81f31\u51046\u5343\u842c\u5e74\u524d\u8207\u96d9\u5b50\u8449\u690d\u7269\u5206\u96e2\uff0c\u5176\u679c\u5be6\u6210\u719f\u5247\u540c\u6642\u5229\u7528\u4e86\u958b\u82b1\u548c\u63a7\u88fd\u8870\u8001\u9019\u5169\u7a2e\u57fa\u56e0\u3002\u96d9\u5b50\u8449\u679c\u5be6\u4e2d\u7684\u897f\u74dc\u3001\u9752\u74dc\u3001\u8461\u8404\u548c\u58eb\u591a\u5564\u68a8\u5247\u9032\u5316\u51fa\u4e00\u5957\u4e0d\u4f9d\u8cf4\u4e59\u70ef\u7684\u8abf\u63a7\u679c\u5be6\u6210\u719f\u7684\u6a5f\u5236\u3002&nbsp;<\/p><p>\u7814\u7a76\u5718\u968a\u66f4\u767c\u73fe\u8868\u89c0\u57fa\u56e0\u7d44H3K27me3\u5728\u9650\u5236\u8089\u8cea\u679c\u5be6\u6210\u719f\u65b9\u9762\u767c\u63ee\u4e86\u4fdd\u5b88\u7684\u4f5c\u7528\u3002H3K27me3\u662f\u4e00\u7a2e\u6291\u5236\u6027\u7d44\u86cb\u767d\u4fee\u98fe\uff0c\u5728\u52d5\u7269\u6216\u690d\u7269\u4e2d\u90fd\u767c\u73fe\u5b83\u8207\u4e3b\u8981\u767c\u80b2\u57fa\u56e0\u7684\u6c89\u9ed8\u6709\u95dc\u9023\u3002\u5728\u8089\u8cea\u6c34\u679c\u7269\u7a2e\u4e2d\uff0c\u4f7f\u7528\u7a69\u5b9a\u7684\u8868\u89c0\u907a\u50b3\u6a19\u8a18\u5982H3K27me3\u4ee5\u4fdd\u8b49\u679c\u5be6\u6210\u719f\u8def\u5f91\u5728\u56b4\u683c\u7684\u767c\u5c55\u63a7\u5236\u4e0b\u5177\u6709\u986f\u8457\u7684\u9032\u5316\u512a\u52e2\u3002<strong>fruitENCODE<\/strong>\u4ea6\u767c\u73fe\u53e4\u8001\u690d\u7269\u7269\u7a2e\u4e2d\u8207\u6210\u719f\u57fa\u56e0\u7684\u540c\u6e90\u57fa\u56e0\u4e0a\u4e5f\u6709\u985e\u4f3c\u7684H3K27me3\u6a19\u8a18\u3002\u9019\u8aaa\u660e\u5728\u9032\u5316\u904e\u7a0b\u4e2d\uff0c\u4e00\u4e9b\u679c\u5be6\u5982\u8543\u8304\u3001\u6843\u548c\u9999\u8549\u4e0d\u55ae\u52ab\u6301\u4e86\u5176\u7956\u5148\u88ab\u5b50\u690d\u7269\u7684\u57fa\u56e0\uff0c\u9084\u6cbf\u7528\u4e86\u5b83\u5011\u7684\u8868\u89c0\u907a\u50b3\u6a19\u8a18\u4f86\u63a7\u5236\u6210\u719f\u3002&nbsp;<\/p><p>\u937e\u601d\u6797\u6559\u6388\u8868\u793a\uff1a\u300c\u900f\u904e\u5206\u679011\u7a2e\u8089\u8cea\u679c\u5be6\u57fa\u56e0\u7d44\u5167\u7684\u300e\u5783\u573eDNA\u300f\uff0c\u5927\u5927\u589e\u52a0\u6211\u5011\u5c0d\u8abf\u7bc0\u679c\u5be6\u6210\u719f\u6a5f\u5236\u7684\u7406\u89e3\u3002\u672a\u4f86\u6211\u5011\u7d42\u6709\u53ef\u80fd\u8a2d\u8a08\u7279\u5b9a\u57fa\u56e0\u7684\u8abf\u63a7\u539f\u4ef6\uff0c\u4ee5\u63a7\u5236\u5176\u8868\u9054\uff0c\u5f9e\u800c\u6539\u5584\u6c34\u679c\u7684\u71df\u990a\u50f9\u503c\u3001\u8ce3\u76f8\u53ca\u4fdd\u9bae\u671f\u3002\u300d<strong>&nbsp;<\/strong><\/p><p><strong>\u6709\u95dc<\/strong><strong>fruitENCODE<\/strong><\/p><p>\u8089\u8cea\u6c34\u679c\u6210\u719f\u662f\u4e00\u500b\u4e0d\u53ef\u9006\u8f49\u7684\u767c\u80b2\u904e\u7a0b\uff0c\u5b83\u6703\u6539\u8b8a\u8f09\u6709\u690d\u7269\u5668\u5b98\u7684\u751f\u7406\u548c\u751f\u5316\u7279\u6027\uff0c\u4ee5\u5e6b\u52a9\u7a2e\u5b50\u50b3\u64ad\u3002\u5728\u6a21\u578b\u679c\u5be6\u8543\u8304\u4e2d\uff0c\u5176\u4e59\u70ef\u6fc0\u7d20\u3001\u679c\u5be6\u7279\u7570\u6027\u8f49\u9304\u56e0\u5b50\u53ca\u8868\u89c0\u57fa\u56e0\u7d44\u91cd\u7d44\uff0c\u5171\u540c\u8abf\u7bc0\u5176\u679c\u5be6\u6210\u719f\u904e\u7a0b\u3002\u9019\u500b\u8907\u96dc\u7684\u6210\u719f\u6a5f\u5236\u5c0d\u65bc\u690d\u7269\u9032\u5316\u975e\u5e38\u91cd\u8981\uff0c\u56e0\u610f\u5916\u6fc0\u6d3b\u679c\u5be6\u6210\u719f\uff0c\u4f7f\u679c\u5be6\u88ab\u52d5\u7269\u5403\u6389\uff0c\u6703\u9020\u6210\u4e0d\u5fc5\u8981\u5730\u6d6a\u8cbb\u7a2e\u5b50\u3002\u76f8\u5c0d\u8f03\u70ba\u7a69\u5b9a\u7684\u8868\u89c0\u907a\u50b3\u6a5f\u5236\u53ef\u4f5c\u70ba\u767c\u80b2\u958b\u95dc\uff0c\u9632\u6b62\u679c\u5be6\u5728\u7a2e\u5b50\u6210\u719f\u524d\u6210\u719f\u3002\u53ef\u662f\uff0c\u7531\u65bc\u8089\u8cea\u679c\u5be6\u65bc\u4e0d\u540c\u7684\u690d\u7269\u8b5c\u7cfb\u4e2d\u7368\u7acb\u5730\u9032\u5316\uff0c\u55ae\u9760\u89c0\u5bdf\u8543\u8304\u7684\u60c5\u6cc1\u4f5c\u5176\u4ed6\u7269\u7a2e\u7684\u53c3\u8003\u662f\u4e0d\u5207\u5be6\u969b\u7684\u60f3\u6cd5\u3002\u56e0\u6b64\uff0c<strong>fruitENCODE<\/strong>\u9805\u76ee\u7684\u76ee\u6a19\u4e0d\u50c5\u70ba\u8543\u8304\u7684\u57fa\u56e0\u7d44\u4f5c\u7d9c\u5408\u5206\u6790\u5176\u529f\u80fd\u5143\u7d20\uff0c\u66f4\u5305\u62ec\u591a\u7a2e\u8089\u8cea\u679c\u5be6\u7269\u7a2e\uff0c\u4ee5\u6aa2\u9a57\u679c\u5be6\u6210\u719f\u904e\u7a0b\u7684\u591a\u6a23\u6027\u3002&nbsp;<\/p><p>\u8a73\u60c5\u8acb\u700f\u89bd\uff1a<a 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