{"id":237630,"date":"2026-06-29T10:23:35","date_gmt":"2026-06-29T02:23:35","guid":{"rendered":"https:\/\/www.cpr.cuhk.edu.hk\/?post_type=press&#038;p=237630"},"modified":"2026-06-29T18:52:47","modified_gmt":"2026-06-29T10:52:47","slug":"cuhk-pioneers-the-all-in-one-pgt-plus-screening-solution-overcoming-conventional-blind-spots-in-hidden-genetic-abnormalities-and-reducing-miscarriage-and-abnormal-pregnancy-risks-in","status":"publish","type":"press","link":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/press\/cuhk-pioneers-the-all-in-one-pgt-plus-screening-solution-overcoming-conventional-blind-spots-in-hidden-genetic-abnormalities-and-reducing-miscarriage-and-abnormal-pregnancy-risks-in\/","title":{"rendered":"\u4e2d\u5927\u5168\u65b0\u4e00\u7ad9\u5f0fPGT-Plus\u65b9\u6848 \u7cbe\u6e96\u8fa8\u8b58\u50b3\u7d71\u6aa2\u6e2c\u4e2d\u8907\u96dc\u57fa\u56e0\u7570\u5e38\u300c\u76f2\u9ede\u300d  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name=\"_ftnref2\">[2]<\/a>\u3002\u9019\u4e9b\u7570\u5e38\u53ef\u5c0e\u81f4\u6d41\u7522\u6216\u56b4\u91cd\u6bcd\u9ad4\u4f75\u767c\u75c7\u3002\u9019\u9805\u66f4\u5168\u9762\u53ca\u7cbe\u6e96\u7684\u4e00\u7ad9\u5f0f\u6aa2\u6e2c\u65b9\u6848\uff0c\u5c07\u63d0\u5347\u73fe\u6642\u7528\u65bc\u4eba\u5de5\u53d7\u5b55\u7684\u80da\u80ce\u690d\u5165\u524d\u907a\u50b3\u5b78\u6aa2\u6e2c\uff08PGT\uff09\u6280\u8853\uff0c\u6709\u52a9\u53ca\u65e9\u767c\u73fe\u554f\u984c\u4e26\u964d\u4f4e\u6d41\u7522\u53ca\u6bcd\u80ce\u9762\u81e8\u7684\u5065\u5eb7\u98a8\u96aa\uff0c\u540c\u6642\u6e1b\u8f15\u5099\u5b55\u5bb6\u5ead\u7684\u8eab\u5fc3\u8ca0\u64d4\u3002\u7814\u7a76\u6210\u679c\u5df2\u65bc\u570b\u969b\u77e5\u540d\u751f\u6b96\u9818\u57df\u671f\u520a\u300a<a href=\"https:\/\/doi.org\/10.1093\/hropen\/hoag044\"><em>Human Reproduction Open<\/em><\/a>\u300b\u4e0a\u767c\u8868\u3002<\/p>\r\n<p><strong>\u50b3\u7d71\u7be9\u67e5\u5b58\u5728\u300c\u76f2\u9ede\u300d<\/strong><strong>\u00a0\u00a0 <\/strong><strong>\u300c\u6b63\u5e38\u300d\u80da\u80ce\u4ea6\u53ef\u5c0e\u81f4\u6d41\u7522<\/strong><\/p>\r\n<p>\u96a8\u8457\u672c\u6e2f\u592b\u5a66\u751f\u80b2\u5e74\u9f61\u5ef6\u5f8c\uff0c\u5c0b\u6c42\u4eba\u5de5\u53d7\u5b55\u7684\u5bb6\u5ead\u6578\u91cf\u9010\u5e74\u589e\u52a0\uff0c\u60df\u53cd\u8986\u6d41\u7522\u8207\u80da\u80ce\u8457\u5e8a\u5931\u6557\u7684\u60c5\u6cc1\uff0c\u5f80\u5f80\u4ee4\u8a31\u591a\u5bb6\u5ead\u627f\u53d7\u6c89\u91cd\u7684\u7d93\u6fdf\u8ca0\u64d4\u8207\u5fc3\u7406\u58d3\u529b\u3002PGT\u662f\u4fdd\u969c\u80da\u80ce\u5065\u5eb7\u7684\u95dc\u9375\uff0c\u80fd\u5728\u80da\u80ce\u690d\u5165\u6bcd\u9ad4\u524d\uff0c\u7be9\u67e5\u5177\u6709\u67d3\u8272\u9ad4\u6216\u55ae\u57fa\u56e0\u7570\u5e38\u7684\u80da\u80ce\u3002<\/p>\r\n<p>\u73fe\u6709\u5e38\u898f\u6aa2\u6e2c\u5305\u62ecPGT-A\u3001PGT-M\u4ee5\u53caPGT-SR<a href=\"#_ftn3\" name=\"_ftnref3\">[3]<\/a>\u3002\u7136\u800c\uff0c\u9019\u4e9b\u65b9\u6cd5\u4e3b\u8981\u91dd\u5c0d\u7279\u5b9a\u907a\u50b3\u554f\u984c\u9032\u884c\u55ae\u9805\u6aa2\u67e5\uff0c\u5728\u61c9\u5c0d\u90e8\u5206\u8907\u96dc\u7570\u5e38\u6642\u5b58\u5728\u6280\u8853\u76f2\u9ede\u3002\u7576\u80da\u80ce\u51fa\u73fe\u4e09\u500d\u9ad4\u53ca\u5168\u57fa\u56e0\u7d44\u55ae\u89aa\u4f86\u6e90\u7570\u5e38\u6642\uff0c\u90e8\u5206\u5e38\u898f\u6aa2\u6e2c\u65b9\u6cd5\u672a\u5fc5\u80fd\u5b8c\u5168\u8b58\u5225\uff0c\u751a\u81f3\u53ef\u80fd\u5c07\u53d7\u5f71\u97ff\u80da\u80ce\u8aa4\u5224\u70ba\u6b63\u5e38\u3002\u9019\u4e9b\u96b1\u85cf\u907a\u50b3\u7f3a\u9677\u6703\u5f15\u767c\u65e9\u671f\u6d41\u7522\u3001\u7121\u6545\u7d42\u6b62\u598a\u5a20\u6216\u5c0e\u81f4\u80ce\u5152\u767c\u80b2\u7570\u5e38\uff1b\u56b4\u91cd\u6642\u66f4\u53ef\u80fd\u5c0e\u81f4\u5b55\u5a66\u51fa\u73fe\u300c\u8461\u8404\u80ce\u300d<a href=\"#_ftn4\" name=\"_ftnref4\">[4]<\/a>\u53ca\u300c\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5\u300d<a href=\"#_ftn5\" name=\"_ftnref5\">[5]<\/a>\u7b49\u56b4\u91cd\u4f75\u767c\u75c7\uff0c\u76f4\u63a5\u5a01\u8105\u5b55\u5a66\u5065\u5eb7\u3002<\/p>\r\n<p><strong>\u9996\u5275<\/strong><strong>PGT-Plus<\/strong><strong>\u6574\u5408\u5206\u6790<\/strong><strong> \u00a0<\/strong><strong>\u4e00\u7ad9\u5f0f\u7cbe\u6e96\u7be9\u67e5\u96b1\u853d\u907a\u50b3\u7570\u5e38<\/strong><strong>\u00a0 <\/strong>\u00a0\u00a0\u00a0<strong>\u00a0<\/strong><\/p>\r\n<p>\u7814\u7a76\u5718\u968a\u9996\u5148\u900f\u904e\u591a\u7a2e\u6a19\u6e96\u80da\u80ce\u6aa2\u6e2c\u6280\u8853\uff0c\u5206\u6790\u5df2\u77e5\u5e36\u6709\u907a\u50b3\u7570\u5e38\u7684\u7d30\u80de\u6a23\u672c\uff0c\u518d\u8207PGT-Plus\u7684\u7d50\u679c\u9032\u884c\u6bd4\u8f03\u53ca\u540c\u6b65\u5206\u6790\uff0c\u4ee5\u8a55\u4f30\u5176\u6e96\u78ba\u6027\u53ca\u6aa2\u6e2c\u80fd\u529b\u3002\u7814\u7a76\u7d50\u679c\u986f\u793a\uff0cPGT-Plus\u6574\u5408\u5e38\u898f\u6aa2\u6e2c\u53ca\u55ae\u6838\u82f7\u9178\u591a\u614b\u6027\uff08SNP\uff09\u57fa\u56e0\u5206\u6790\u6280\u8853\uff0c\u5177\u4ee5\u4e0b\u6548\u76ca\uff1a<\/p>\r\n<ul>\r\n\t<li><strong>\u66f4\u7cbe\u7c21\u3001\u66f4\u5168\u9762\uff1a<\/strong>\u57281,049 \u500b\u56ca\u80da\u4e2d\uff0cPGT-Plus\u900f\u904e\u55ae\u4e00\u6aa2\u6e2c\u6d41\u7a0b\uff0c\u8f03\u50b3\u7d71\u6aa2\u6e2c\u984d\u5916\u6aa2\u6e2c\u51fa2%\u7684\u7570\u5e38\u500b\u6848\uff0c\u5305\u62ec0.8%\u7684\u4e09\u500d\u9ad4\u53ca1.4% \u7684\u55ae\u89aa\u4f86\u6e90\u57fa\u56e0\u7d44\u7570\u5e38\u3002<\/li>\r\n\t<li><strong>\u63d0\u5347<\/strong><strong>\u80da\u80ce\u7be9\u9078\u6e96\u78ba\u5ea6\uff1a<\/strong>\u5728\u539f\u5148\u7d93\u50b3\u7d71\u6280\u8853\u8a55\u4f30\u70ba\u6b63\u5e38\u3001\u4f46\u690d\u5165\u5f8c\u672a\u80fd\u9806\u5229\u767c\u5c55\u6210\u5065\u5eb7\u598a\u5a20\u7684258\u500b\u80da\u80ce\u4e2d\uff0cPGT-Plus\u6210\u529f\u8b58\u5225\u51fa\u8d85\u904e3%\u5e36\u6709\u4e09\u500d\u9ad4\u6216\u55ae\u89aa\u4f86\u6e90\u57fa\u56e0\u7d44\u7570\u5e38\u7684\u80da\u80ce\u3002<\/li>\r\n\t<li><strong>\u88dc\u8db3\u6f5b\u5728\u6f0f\u6aa2\u60c5\u6cc1\uff1a<\/strong>\u5728\u651c\u5e36\u300c\u67d3\u8272\u9ad4\u7d50\u69cb\u7570\u5e38\u300d<a href=\"#_ftn6\" name=\"_ftnref6\">[6]<\/a>\u7684\u592b\u5a66\u4e2d\uff0c\u5c0d\u65bc\u88ab\u50b3\u7d71\u6280\u8853\u5224\u5b9a\u70ba\u300c\u67d3\u8272\u9ad4\u7d50\u69cb\u6b63\u5e38\u300d\u7684\u80da\u80ce\uff0cPGT-Plus\u5728\u7d04\u6bcf\u5169\u500b\u80da\u80ce\u4e2d\u6aa2\u6e2c\u51fa\u4e00\u500b\u5be6\u969b\u4e0a\u5e36\u6709\u300c\u67d3\u8272\u9ad4\u6613\u4f4d\u300d<a href=\"#_ftn7\" name=\"_ftnref7\">[7]<\/a>\u7684\u80da\u80ce\u3002<\/li>\r\n<\/ul>\r\n<p>PGT-Plus\u6709\u671b\u70ba\u5177\u907a\u50b3\u75be\u75c5\u6216\u67d3\u8272\u9ad4\u7d50\u69cb\u554f\u984c\u98a8\u96aa\u7684\u5bb6\u5ead\u63d0\u4f9b\u66f4\u7cbe\u6e96\u7684\u65b9\u6848\uff0c\u7be9\u9078\u51fa\u6c92\u6709\u907a\u50b3\u7d50\u69cb\u7570\u5e38\u7684\u5065\u5eb7\u80da\u80ce\uff0c\u963b\u6b62\u907a\u50b3\u6027\u6d41\u7522\u7684\u60e1\u6027\u5faa\u74b0\u3002<\/p>\r\n<p>\u4e2d\u5927\u91ab\u5b78\u9662\u5a66\u7522\u79d1\u5b78\u7cfb\u7814\u7a76\u52a9\u7406\u6559\u6388<strong>\u5468\u6d77\u9375\u535a\u58eb<\/strong>\u6307\u51fa\uff1a\u300c\u900f\u904e 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