{"id":113839,"date":"2021-05-06T15:10:49","date_gmt":"2021-05-06T07:10:49","guid":{"rendered":"https:\/\/www.cpr.cuhk.edu.hk\/?post_type=press&p=113839"},"modified":"2021-05-10T12:34:26","modified_gmt":"2021-05-10T04:34:26","slug":"a-global-study-led-by-cu-medicine-and-hkumed-discovers-a-hepatitis-c-virus-drug-as-potent-treatment-for-covid-19","status":"publish","type":"press","link":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/press\/a-global-study-led-by-cu-medicine-and-hkumed-discovers-a-hepatitis-c-virus-drug-as-potent-treatment-for-covid-19\/","title":{"rendered":"\u4e2d\u5927\u8207\u6e2f\u5927\u91ab\u5b78\u9662\u5e36\u9818\u570b\u969b\u79d1\u7814\u5718\u968a\u767c\u73fe\u4e19\u809d\u85e5\u7269\u53ef\u6cbb\u65b0\u51a0\u80ba\u708e"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","tags":[],"class_list":["post-113839","press","type-press","status-publish","hentry"],"acf":{"title_alt":"","sub_title_alt":"","press_date":"20210510","keep":false,"details":"

\u7531\u9999\u6e2f\u4e2d\u6587\u5927\u5b78\uff08\u4e2d\u5927\uff09\u91ab\u5b78\u9662\u53ca\u9999\u6e2f\u5927\u5b78\u674e\u5609\u8aa0\u91ab\u5b78\u9662\uff08\u6e2f\u5927\u91ab\u5b78\u9662\uff09\u9818\u5c0e\u7684\u570b\u969b\u79d1\u7814\u5718\u968a\uff0c\u767c\u73fe\u4e00\u7a2e\u66fe\u7528\u65bc\u6cbb\u7642\u4e19\u578b\u809d\u708e\u7684\u85e5\u7269\u300c\u53f8\u7f8e\u5339\u97cb\uff08Simeprevir\uff09\u300d\u53ef\u6709\u6548\u6291\u5236\u65b0\u578b\u51a0\u72c0\u75c5\u6bd2\u7e41\u6b96\uff0c\u8207\u73fe\u6642\u7528\u65bc\u6cbb\u7642\u65b0\u51a0\u80ba\u708e\u7684\u6297\u75c5\u6bd2\u85e5\u7269\u300c\u745e\u5fb7\u897f\u97cb\uff08Remdesivir\uff09\u300d\u4e00\u4f75\u4f7f\u7528\u66f4\u53ef\u4ee5\u7522\u751f\u5354\u540c\u6548\u61c9\uff0c\u63d0\u5347\u6297\u75c5\u6bd2\u7684\u6210\u6548\u3002\u7814\u7a76\u5718\u968a\u8868\u793a\u53f8\u7f8e\u5339\u97cb\u662f\u73fe\u6642\u552f\u4e00\u540c\u6642\u91dd\u5c0d\u591a\u65bc\u4e00\u500b\u65b0\u51a0\u75c5\u6bd2\u86cb\u767d\u7684\u6297\u75c5\u6bd2\u85e5\u7269\uff0c\u4ee3\u8868\u5373\u4f7f\u5176\u4e2d\u4e00\u500b\u86cb\u767d\u51fa\u73fe\u8b8a\u7570\uff0c\u4ecd\u53ef\u900f\u904e\u6291\u5236\u53e6\u4e00\u500b\u86cb\u767d\u4ee5\u767c\u63ee\u4f5c\u7528\uff0c\u7522\u751f\u6297\u85e5\u6027\u75c5\u6bd2\u8b8a\u7570\u7684\u6a5f\u6703\u4ea6\u8f03\u4f4e\uff0c\u65e5\u5f8c\u6216\u53ef\u6210\u70ba\u65b0\u51a0\u85e5\u7269\u7814\u767c\u7684\u65b0\u65b9\u5411\u3002\u7814\u7a76\u7d50\u679c\u5df2\u520a\u767b\u65bc\u570b\u969b\u77e5\u540d\u5316\u5b78\u671f\u520a\u300aACS Central Science<\/em><\/strong>\u300b\u3002\uff08\u6309\u6b64\u700f\u89bd\u671f\u520a\u6587\u7ae0<\/a>\uff09<\/p>\r\n

\u53f8\u7f8e\u5339\u97cb\u80fd\u5920\u91dd\u5c0d<\/strong>\u5169<\/strong>\u500b\u65b0\u51a0\u75c5\u6bd2\u86cb\u767d<\/strong><\/p>\r\n

\u81ea2020\u5e74\u521d\uff0c\u4e2d\u5927\u91ab\u5b78\u9662\u85e5\u5291\u5b78\u9662\u52a9\u7406\u6559\u6388\u5433\u6ff0\u9f8d\u6559\u6388\u8207\u6e2f\u5927\u91ab\u5b78\u9662\u516c\u5171\u885e\u751f\u5b78\u9662\u526f\u6559\u6388\u9673\u5fd7\u5049\u535a\u58eb\uff0c\u806f\u540c\u8d85\u904e30\u4f4d\u672c\u5730\u53ca\u6d77\u5916\u5be6\u9a57\u5ba4\u7684\u79d1\u7814\u4eba\u54e1\uff08\u5305\u62ec\u5167\u5730\u3001\u7f8e\u570b\u3001\u6cd5\u570b\u3001\u5fb7\u570b\u3001\u5357\u97d3\u53ca\u53f0\u7063\uff09\uff0c\u904b\u7528\u751f\u7269\u5316\u5b78\u3001\u7d30\u80de\u751f\u7269\u5b78\u53ca\u8a08\u7b97\u6a5f\u5316\u5b78\u7b49\u6280\u8853\uff0c\u5728\u7d30\u80de\u6a21\u578b\u4e2d\u6e2c\u8a66\u591a\u7a2e\u5df2\u7d93\u7372\u7f8e\u570b\u98df\u54c1\u85e5\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u4f7f\u7528\u7684\u6297\u75c5\u6bd2\u85e5\u7269\uff0c\u5408\u529b\u5c0b\u627e\u80fd\u6709\u6548\u6297\u8861\u65b0\u51a0\u80ba\u708e\u7684\u85e5\u7269\u3002\u5718\u968a\u767c\u73fe\u4e19\u809d\u85e5\u53f8\u7f8e\u5339\u97cb\u80fd\u6709\u6548\u540c\u6642\u6291\u5236\u5169\u500b\u91cd\u8981\u86cb\u767d\uff0c\u5206\u5225\u662f\u8ca0\u8cac\u75c5\u6bd2\u591a\u80bd\u5207\u5272\u7684\u4e3b\u86cb\u767d\u9176Mpro<\/sup>\u548c\u8ca0\u8cac\u75c5\u6bd2\u8907\u88fd\u7684RNA\u805a\u5408\u9176\uff0c\u9019\u662f\u73fe\u6642\u552f\u4e00\u53ef\u4ee5\u540c\u6642\u91dd\u5c0d\u591a\u65bc\u4e00\u500b\u65b0\u51a0\u75c5\u6bd2\u86cb\u767d\u7684\u6297\u75c5\u6bd2\u85e5\u7269\u3002<\/p>\r\n

\u9818\u5c0e\u6b64\u9805\u7814\u7a76\u7684\u4e2d\u5927\u91ab\u5b78\u9662\u85e5\u5291\u5b78\u9662\u52a9\u7406\u6559\u6388\u5433\u6ff0\u9f8d\u6559\u6388<\/strong>\u8868\u793a\uff1a\u300c\u53f8\u7f8e\u5339\u97cb\u662f\u4e00\u7a2e\u6297\u75c5\u6bd2\u85e5\u7269\uff0c\u4e3b\u8981\u7528\u65bc\u6cbb\u7642\u4e19\u578b\u809d\u708e\uff0c\u900f\u904e\u6291\u5236\u75c5\u6bd2\u7684\u86cb\u767d\u9176\u6d3b\u6027\u4f86\u963b\u6b62\u75c5\u6bd2\u8907\u88fd\u589e\u751f\u3002\u96d6\u7136\u53f8\u7f8e\u5339\u97cb\u8fd1\u5e74\u5df2\u7d93\u88ab\u5176\u4ed6\u4e19\u809d\u85e5\u7269\u53d6\u4ee3\uff0c\u4f46\u7531\u65bc\u5b83\u5df2\u901a\u904eFDA\u5be9\u6279\uff0c\u91cd\u65b0\u767c\u6398\u5176\u4ed6\u6f5b\u5728\u7528\u9014\uff0c\u53ef\u7e2e\u77ed\u81e8\u5e8a\u7814\u7a76\u6642\u9593\u3002\u9019\u662f\u4e00\u500b\u975e\u5e38\u6709\u524d\u666f\u53ca\u4ee4\u4eba\u9f13\u821e\u7684\u767c\u73fe\u3002\u6b64\u5916\uff0c\u7531\u65bc\u65b0\u51a0\u75c5\u6bd2\u540c\u6642\u51fa\u73fe\u4e3b\u86cb\u767d\u9176Mpro<\/sup>\u548cRNA\u805a\u5408\u9176\u8b8a\u7570\u7684\u6a5f\u6703\u6975\u5fae\uff0c\u5373\u4f7f\u5176\u4e2d\u4e00\u500b\u86cb\u767d\u51fa\u73fe\u8b8a\u7570\uff0c\u4ecd\u53ef\u900f\u904e\u6291\u5236\u53e6\u4e00\u500b\u86cb\u767d\u4ee5\u767c\u63ee\u4f5c\u7528\uff0c\u7522\u751f\u6297\u85e5\u6027\u75c5\u6bd2\u8b8a\u7570\u7684\u6a5f\u6703\u4ea6\u8f03\u4f4e\u3002\u300d\u00a0<\/strong><\/p>\r\n

\u914d\u5408\u745e\u5fb7<\/strong>\u897f\u97cb<\/strong>\u4f7f\u7528\u589e\u6cbb<\/strong>\u7642<\/strong>\u65b0\u51a0\u6210\u6548<\/strong><\/p>\r\n

\u96d6\u7136\u745e\u5fb7\u897f\u97cb\u53ef\u6709\u6548\u6cbb\u7642\u65b0\u51a0\u80ba\u708e\uff0c\u4f46\u5b83\u53ea\u80fd\u6291\u5236\u4e00\u500b\u75c5\u6bd2\u86cb\u767d\uff0c\u4e00\u65e6\u8a72\u86cb\u767d\u8b8a\u7a2e\uff0c\u53ef\u80fd\u4ee4\u75c5\u6bd2\u7522\u751f\u6297\u85e5\u6027\u3002\u6b64\u5916\uff0c\u745e\u5fb7\u897f\u97cb\u5c0d\u63a7\u5236\u56b4\u91cd\u75c5\u4f8b\u7684\u6548\u679c\u4e26\u4e0d\u986f\u8457\u3002<\/p>\r\n

\u6e2f\u5927\u516c\u5171\u885e\u751f\u5b78\u9662\u526f\u6559\u6388\u9673\u5fd7\u5049\u535a\u58eb<\/strong>\u8868\u793a\uff1a\u300c\u6211\u5011\u4ea6\u5c0d\u53f8\u7f8e\u5339\u97cb\u8207\u745e\u5fb7\u897f\u97cb\u7684\u6548\u7528\u9032\u884c\u6e2c\u8a66\uff0c\u767c\u73fe\u540c\u6642\u4f7f\u7528\u6b64\u5169\u7a2e\u85e5\u7269\u6703\u7522\u751f\u5354\u540c\u4f5c\u7528\u3002\u65bc\u6e2f\u5927\u751f\u7269\u5b89\u5168\u4e09\u7d1a\u5be6\u9a57\u5ba4\u9032\u884c\u7684\u75c5\u6bd2\u611f\u67d3\u5be6\u9a57\u986f\u793a\uff0c\u53ea\u9700\u4f7f\u7528\u5291\u91cf3.3\u5fae\u83ab\u8033\uff08\u03bcM\uff09\u7684\u53f8\u7f8e\u5339\u97cb\u548c\u745e\u5fb7\u897f\u97cb\uff0c\u5df2\u53ef\u5927\u5e45\u6291\u5236\u75c5\u6bd2\u8907\u88fd\uff0c\u6bd4\u55ae\u7368\u4f7f\u7528\u745e\u5fb7\u897f\u97cb\u7684\u6548\u529b\u9ad8\u51fa\u8d85\u904e\u4e00\u767e\u500d\u3002\u300d<\/p>\r\n

\u5433\u6559\u6388\u88dc\u5145\uff1a\u300c\u900f\u904e\u4e86\u89e3\u53f8\u7f8e\u5339\u97cb\u5728\u55ae\u7368\u6216\u806f\u5408\u4f7f\u7528\u6642\u6291\u5236\u75c5\u6bd2\u86cb\u767d\u7684\u5206\u5b50\u6a5f\u5236\uff0c\u5c07\u70ba\u5c0d\u6297\u65b0\u51a0\u75c5\u6bd2\u5e36\u4f86\u66f4\u591a\u7814\u7a76\u65b9\u5411\u3002\u79d1\u5b78\u7121\u7586\u754c\uff0c\u5728\u6b64\u6211\u5011\u611f\u8b1d\u4f86\u81ea\u4e0d\u540c\u5730\u57df\u3001\u5b78\u79d1\u7684\u79d1\u7814\u4eba\u54e1\u53ca\u5b78\u8005\u53c3\u8207\u6b64\u7814\u7a76\uff0c\u6574\u500b\u5718\u968a\u7684\u5408\u4f5c\u7cbe\u795e\u3001\u6c7a\u5fc3\u548c\u6bc5\u529b\u662f\u6211\u5011\u9019\u6b21\u7814\u7a76\u6210\u679c\u7684\u91cd\u8981\u95dc\u9375\u3002\u300d<\/p>\r\n

\u4e2d\u5927\u4f55\u9d3b\u71ca\u547c\u5438\u7cfb\u7d71\u79d1\u8b1b\u5ea7\u6559\u6388\u8a31\u6a39\u660c\u6559\u6388<\/strong>\u8868\u793a\uff1a\u300c\u9678\u7e8c\u9762\u4e16\u7684\u65b0\u51a0\u80ba\u708e\u75ab\u82d7\u70ba\u6297\u75ab\u5e36\u4f86\u66d9\u5149\uff0c\u4f46\u662f\u4e16\u754c\u5404\u5730\u7684\u611f\u67d3\u4eba\u6578\u4ecd\u7136\u6301\u7e8c\u9ad8\u4f01\u3002\u96a8\u8457\u75c5\u6bd2\u8b8a\u7a2e\u958b\u59cb\u6d6e\u73fe\uff0c\u73fe\u6709\u7684\u75ab\u82d7\u53ca\u85e5\u7269\u4e26\u4e0d\u4e00\u5b9a\u80fd\u5920\u6709\u6548\u5730\u8207\u4e4b\u6297\u8861\u3002\u56de\u9996\u904e\u53bb\u4e8c\u5341\u5e74\uff0c\u51a0\u72c0\u75c5\u6bd2\u5df2\u7d93\u53cd\u8986\u5f15\u8d77\u4e86\u6578\u6b21\u5927\u6d41\u884c\uff0c\u9019\u8868\u660e\u8a72\u75c5\u6bd2\u53ef\u80fd\u6301\u7e8c\u5730\u5a01\u8105\u4eba\u985e\u5065\u5eb7\uff0c\u5e36\u4f86\u4e0b\u4e00\u5834\u6d41\u884c\u75c5\uff0c\u56e0\u6b64\u6211\u5011\u5fc5\u9808\u7e7c\u7e8c\u7814\u767c\u80fd\u5920\u5ee3\u6cdb\u5c0d\u6297\u51a0\u72c0\u75c5\u6bd2\u7684\u85e5\u7269\u3002\u300d<\/p>","show_as_achievement":true,"achievement_category":["staff"],"show_as_clarification":false,"show_as_announcement":false,"photos":[{"photo":113834,"caption":"\u7531\u4e2d\u5927\u91ab\u5b78\u9662\u53ca\u6e2f\u5927\u91ab\u5b78\u9662\u9818\u5c0e\u7684\u570b\u969b\u79d1\u7814\u5718\u968a\uff0c\u767c\u73fe\u4e00\u7a2e\u66fe\u7528\u65bc\u6cbb\u7642\u4e19\u578b\u809d\u708e\u7684\u85e5\u7269\u300c\u53f8\u7f8e\u5339\u97cb\u300d\u53ef\u6709\u6548\u6291\u5236\u65b0\u578b\u51a0\u72c0\u75c5\u6bd2\u7e41\u6b96\uff0c\u8207\u73fe\u6642\u7528\u65bc\u6cbb\u7642\u65b0\u51a0\u80ba\u708e\u7684\u6297\u75c5\u6bd2\u85e5\u7269\u300c\u745e\u5fb7\u897f\u97cb\u300d\u4e00\u4f75\u4f7f\u7528\u66f4\u53ef\u4ee5\u7522\u751f\u5354\u540c\u6548\u61c9\uff0c\u63d0\u5347\u6297\u75c5\u6bd2\u7684\u6210\u6548\u3002\r\n\uff08\u53f3\u8d77\uff09\u4e2d\u5927\u4f55\u9d3b\u71ca\u547c\u5438\u7cfb\u7d71\u79d1\u8b1b\u5ea7\u6559\u6388\u8a31\u6a39\u660c\u6559\u6388\u3001\u4e2d\u5927\u91ab\u5b78\u9662\u85e5\u5291\u5b78\u9662\u52a9\u7406\u6559\u6388\u5433\u6ff0\u9f8d\u6559\u6388\u3001\u6e2f\u5927\u516c\u5171\u885e\u751f\u5b78\u9662\u526f\u6559\u6388\u9673\u5fd7\u5049\u535a\u58eb\u53ca\u6e2f\u5927\u516c\u5171\u885e\u751f\u5b78\u9662\u52a9\u7406\u6559\u6388\uff08\u7814\u7a76\uff09\u8a31\u4f69\u8335\u535a\u58eb"},{"photo":113836,"caption":"\u5433\u6ff0\u9f8d\u6559\u6388\u8868\u793a\uff0c\u900f\u904e\u4e86\u89e3\u53f8\u7f8e\u5339\u97cb\u5728\u55ae\u7368\u6216\u806f\u5408\u4f7f\u7528\u6642\u6291\u5236\u75c5\u6bd2\u86cb\u767d\u7684\u5206\u5b50\u6a5f\u5236\uff0c\u5c07\u70ba\u5c0d\u6297\u65b0\u51a0\u75c5\u6bd2\u5e36\u4f86\u66f4\u591a\u7814\u7a76\u65b9\u5411\u3002"},{"photo":113837,"caption":"\u9673\u5fd7\u5049\u535a\u58eb\u8868\u793a\uff0c\u5718\u968a\u5df2\u7d93\u958b\u5c55\u52d5\u7269\u6a21\u578b\u5be6\u9a57\uff0c\u671f\u671b\u6700\u5feb\u534a\u5e74\u53ef\u4ee5\u6709\u521d\u6b65\u7d50\u679c\u3002"},{"photo":113838,"caption":"\u8a31\u6a39\u660c\u6559\u6388\u8868\u793a\uff0c\u5018\u82e5\u53f8\u7f8e\u5339\u97cb\u7d93\u81e8\u5e8a\u5be6\u9a57\u8b49\u5be6\u6709\u6548\u80fd\u5920\u6291\u5236\u65b0\u51a0\u75c5\u6bd2\uff0c\u6df7\u5408\u745e\u5fb7\u897f\u97cb\u4f7f\u7528\uff0c\u6216\u53ef\u7e2e\u77ed\u7642\u7a0b\uff0c\u4e26\u9032\u4e00\u6b65\u63a2\u7a76\u6e1b\u4f4e\u6b7b\u4ea1\u7387\u7b49\u5176\u4ed6\u53ef\u80fd\u6027\u3002"}],"attachments":null,"video_source":"","video_file":"","add_play_button":false,"video_caption":"","show_migration":false,"original_id":0,"photos_original":null,"attachments_original":null},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/wp-json\/wp\/v2\/press\/113839","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/wp-json\/wp\/v2\/press"}],"about":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/wp-json\/wp\/v2\/types\/press"}],"version-history":[{"count":7,"href":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/wp-json\/wp\/v2\/press\/113839\/revisions"}],"predecessor-version":[{"id":113960,"href":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/wp-json\/wp\/v2\/press\/113839\/revisions\/113960"}],"wp:attachment":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/wp-json\/wp\/v2\/media?parent=113839"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/wp-json\/wp\/v2\/tags?post=113839"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}