{"id":113420,"date":"2021-04-22T10:56:12","date_gmt":"2021-04-22T02:56:12","guid":{"rendered":"https:\/\/www.cpr.cuhk.edu.hk\/?post_type=press&#038;p=113420"},"modified":"2021-04-26T08:48:23","modified_gmt":"2021-04-26T00:48:23","slug":"cuhk-study-proves-air-pollution-is-strongly-correlated-with-early-atherogenic-process","status":"publish","type":"press","link":"https:\/\/www.cpr.cuhk.edu.hk\/tc\/press\/cuhk-study-proves-air-pollution-is-strongly-correlated-with-early-atherogenic-process\/","title":{"rendered":"\u4e2d\u5927\u7814\u7a76\u8b49\u5be6\u7a7a\u6c23\u6c61\u67d3\u8207\u65e9\u671f\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u75c5\u8b8a\u6709\u5bc6\u5207\u95dc\u9023"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","tags":[],"class_list":["post-113420","press","type-press","status-publish","hentry"],"acf":{"title_alt":"","sub_title_alt":"","press_date":"20210422","keep":false,"details":"<p>\u9999\u6e2f\u4e2d\u6587\u5927\u5b78\uff08\u4e2d\u5927\uff09\u91ab\u5b78\u9662\u7814\u7a76\u8b49\u5be6\uff0c\u751f\u6d3b\u5728\u5fae\u7d30\u61f8\u6d6e\u7c92\u5b50\uff08PM2.5\uff09\u9ad8\u6fc3\u5ea6\u5730\u5340\u7684\u4eba\u58eb\uff0c\u5176\u300c\u9838\u52d5\u8108\u5167\u819c\u4e2d\u5c64\u539a\u5ea6\uff08IMT\uff09\u300d\u589e\u52a08%\u3002IMT\u88ab\u8996\u70ba\u65e9\u671f\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u7684\u6307\u6a19\uff0c\u6b64\u6578\u5b57\u53cd\u6620\u4e2d\u98a8\u548c\u6025\u6027\u5fc3\u81df\u75c5\u7684\u98a8\u96aa\u5206\u5225\u589e\u52a0\u903e\u56db\u6210\u3002\u76f8\u95dc\u7814\u7a76\u7d50\u679c\u5df2\u65bc\u671f\u520a\u300aInternational Journal of Epidemiology\u300b<sup>1<\/sup>\u767c\u8868\u3002<\/p>\r\n<p>\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u70ba\u73fe\u4eca\u793e\u6703\u6700\u5e38\u898b\u7684\u5fc3\u8166\u8840\u7ba1\u75be\u75c5\uff0c\u4ea6\u662f\u5168\u7403\u982d\u865f\u75be\u75c5\u6bba\u624b\u3002\u9664\u4e86\u80a5\u80d6\u3001\u9ad8\u8840\u58d3\u3001\u8840\u8102\u7570\u5e38\u3001\u7cd6\u5c3f\u75c5\u3001\u7159\u8349\u4f7f\u7528\u548c\u7f3a\u4e4f\u904b\u52d5\u7b49\u50b3\u7d71\u9ad8\u5371\u56e0\u7d20\u5916\uff0c\u6709\u5927\u91cf\u7684\u6d41\u884c\u75c5\u5b78\u8b49\u64da\u986f\u793a\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u767c\u75c5\u7387\u548c\u6b7b\u4ea1\u7387\u8207PM2.5\u7a7a\u6c23\u6c61\u67d3\u6709\u95dc\uff0c\u60df\u554f\u984c\u904e\u53bb\u88ab\u56b4\u91cd\u4f4e\u4f30\u3002<\/p>\r\n<p><strong>\u7a7a\u6c23\u6c61\u67d3\u8207\u65b0\u51a0\u80ba\u708e\u7684\u4e92\u52d5\u6548\u61c9<\/strong><\/p>\r\n<p>\u65b0\u51a0\u80ba\u708e\u5927\u6d41\u884c\u671f\u9593\uff0c\u5fc3\u81df\u75c5\u548c\u4e2d\u98a8\u60a3\u8005\u7684\u6b7b\u4ea1\u4eba\u6578\u5927\u5e45\u589e\u52a0\uff0c\u63d0\u793a\u7a7a\u6c23\u6c61\u67d3\u53ca\u65b0\u51a0\u80ba\u708e\u7684\u4e92\u52d5\u6548\u61c9\u3002\u591a\u500b\u570b\u969b\u7d44\u7e54\u5305\u62ec\u4e16\u754c\u5fc3\u81df\u806f\u5408\u6703\u3001\u7f8e\u570b\u5fc3\u81df\u75c5\u5b78\u6703\u3001\u7f8e\u570b\u5fc3\u81df\u5354\u6703\u548c\u6b50\u6d32\u5fc3\u81df\u75c5\u5b78\u6703\u5728\u4eca\u5e741\u6708\u767c\u8868\u7684\u806f\u5408\u8072\u660e<sup>2<\/sup>\u4e2d\u6307\u51fa\uff0c\u7a7a\u6c23\u6c61\u67d3\u6703\u589e\u52a0\u5fc3\u81df\u75c5\u3001\u4e2d\u98a8\u3001\u7cd6\u5c3f\u75c5\u548c\u547c\u5438\u9053\u75be\u75c5\u7684\u98a8\u96aa\uff0c\u800c\u9019\u4e9b\u6162\u6027\u75c5\u60a3\u8005\u611f\u67d3\u65b0\u51a0\u80ba\u708e\u5f8c\u51fa\u73fe\u56b4\u91cd\u5f8c\u679c\u7684\u98a8\u96aa\u8f03\u9ad8\uff0c\u6545\u547c\u7c72\u5168\u7403\u63a1\u53d6\u7dca\u6025\u884c\u52d5\u6e1b\u5c11\u7a7a\u6c23\u6c61\u67d3\uff0c\u4e26\u63a1\u53d6\u6709\u6548\u7684\u9810\u9632\u63aa\u65bd\u3002<\/p>\r\n<p><strong>PM2.5<\/strong><strong>\u7a7a\u6c23\u6c61<\/strong><strong>\u67d3<\/strong><strong>\u53ef\u5f15\u767c\u80ba\u708e<\/strong> <strong>\u7e7c\u800c\u8a98\u767c\u8840\u7ba1\u708e\u75c7\u53ca\u7ca5\u6a23\u786c\u5316<\/strong><\/p>\r\n<p>\u4e2d\u5927\u91ab\u5b78\u9662\u5206\u6790\u4e86\u65bc1996\u81f32007\u5e74\u6536\u96c6\u7684\u7814\u7a76\u6578\u64da\uff0c\u7576\u4e2d\u6d89\u53ca1,656\u540d\u6210\u5e74\u4eba\u3002\u7814\u7a76\u5c0d\u8c61\u4f86\u81ea\u9999\u6e2f\u3001\u6fb3\u9580\u53ca\u5167\u5730\u591a\u500b\u7701\u5e02\u7b49\uff0c\u900f\u904e\u8d85\u8072\u6ce2\u91cf\u5ea6\u4ed6\u5011\u7684\u300c\u624b\u81c2\u52d5\u8108\u8840\u6d41\u4ecb\u5c0e\u64f4\u5f35\uff08FMD\uff09\u300d\u53ca\u300c\u9838\u52d5\u8108\u5167\u819c\u4e2d\u5c64\u539a\u5ea6\uff08IMT\uff09\u300d\u3002IMT\u548cFMD\u90fd\u53ef\u4f5c\u70ba\u65e9\u671f\u8840\u7ba1\u786c\u5316\u6307\u6a19\uff0c\u7528\u4f5c\u9810\u6e2c\u5fc3\u81df\u75c5\u548c\u4e2d\u98a8\u7684\u767c\u751f\u3002<\/p>\r\n<p>\u7814\u7a76\u5718\u968a\u53e6\u900f\u904e\u885b\u661f\u6a21\u578b\u4f30\u7b97\u53c3\u52a0\u8005\u6240\u63a5\u89f8\u7684PM2.5\u6fc3\u5ea6\uff0c\u6309\u5730\u5340\u6c61\u67d3\u7a0b\u5ea6\u5c07\u53c3\u52a0\u8005\u5206\u6210\u4e0d\u540c\u7d44\u5225\u3002\u5718\u968a\u767c\u73fe\u66dd\u9732\u65bc\u6700\u9ad8PM2.5\u6fc3\u5ea6\u7684\u53c3\u52a0\u8005\uff0c\u8207\u6700\u4f4e\u7684\u4e00\u7d44\u76f8\u6bd4\uff0c\u9838\u52d5\u8108IMT\u539a\u5ea6\u591a8%\uff0c\u800cFMD\u7684\u8868\u73fe\u4ea6\u8f03\u5dee\u3002\u8a73\u60c5\u5982\u4e0b\uff1a<\/p>\r\n<table>\r\n<tbody>\r\n<tr>\r\n<td width=\"240\">\r\n<p>&nbsp;<\/p>\r\n<\/td>\r\n<td width=\"204\">\r\n<p>\u6700\u9ad8\u6fc3\u5ea6PM2.5\u7d44\u5225<br \/>\r\n(\u6bcf\u7acb\u65b9\u7c7383.8\u5fae\u514b)<\/p>\r\n<\/td>\r\n<td width=\"196\">\r\n<p>\u6700\u4f4e\u6fc3\u5ea6PM2.5\u7d44\u5225<br \/>\r\n(\u6bcf\u7acb\u65b9\u7c7342.9\u5fae\u514b)<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td width=\"240\">\r\n<p>\u9838\u52d5\u8108\u5167\u819c\u4e2d\u5c64\u539a\u5ea6\uff08IMT\uff09<\/p>\r\n<\/td>\r\n<td width=\"204\">\r\n<p>0.68\u6beb\u7c73<\/p>\r\n<\/td>\r\n<td width=\"196\">\r\n<p>0.63\u6beb\u7c73<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td width=\"240\">\r\n<p>\u624b\u81c2\u52d5\u8108\u8840\u6d41\u4ecb\u5c0e\u64f4\u5f35\uff08FMD*\uff09<\/p>\r\n<\/td>\r\n<td width=\"204\">\r\n<p>7.84%<\/p>\r\n<\/td>\r\n<td width=\"196\">\r\n<p>8.5%<\/p>\r\n<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<p>*<em>FMD<\/em><em>\u70ba\u89e3\u9664\u9589\u585e\u5f8c\u8840\u7ba1\u7684\u6700\u5927\u76f4\u5f91\u8207\u5e73\u5747\u57fa\u7dda\u76f4\u5f91\u4e4b\u9593\u7684\u5dee\u7570\uff0c\u4ee5\u767e\u5206\u6bd4\u8868\u793a\u3002<\/em> <em>FMD <\/em><em>7-10<\/em><em>\uff05\u70ba\u6b63\u5e38\u7bc4<\/em><em>\u570d<\/em><em>\uff0c\u800c\u6578<\/em><em>\u5b57<\/em><em>\u6108\u9ad8\u53cd\u6620\u8840\u7ba1\u6108\u5065\u5eb7\u3002<\/em><\/p>\r\n<p>\u53c3\u8003\u8377\u862d\u4e00\u9805\u8ffd\u8e642\u81f37\u5e74\u7684\u7814\u7a76\u5831\u544a<sup>3<\/sup>\uff0c8%\u7684 IMT\u5dee\u7570\u6703\u4ee4\u4e2d\u98a8\u7387\u589e\u52a041%\uff0c\u6025\u6027\u5fc3\u81df\u75c5\u767c\u751f\u6bd4\u7387\u589e\u52a043%\uff0c\u76f8\u7576\u65bc\u7cd6\u5c3f\u75c5\u548c\u975e\u7cd6\u5c3f\u75c5\u6210\u5e74\u4eba\u4e4b\u9593\u6240\u898b\u7684IMT\u5dee\u7570\uff0c\u53cd\u6620PM2.5\u7a7a\u6c23\u6c61\u67d3\u9577\u9060\u800c\u8a00\u5c0d\u5065\u5eb7\u6709\u91cd\u5927\u5f71\u97ff \u3002<\/p>\r\n<p>\u4e2d\u5927\u91ab\u5b78\u9662\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u6559\u6388<strong>\u90ed\u5fd7\u92b3\u6559<\/strong><strong>\u6388<\/strong>\u8868\u793a\uff1a\u300cPM2.5\u7a7a\u6c23\u6c61\u67d3\u53ef\u5f15\u767c\u8f15\u5fae\u7684\u80ba\u90e8\u708e\u75c7\uff0c\u7e7c\u800c\u5c0e\u81f4\u5168\u8eab\u6027\u8840\u7ba1\u708e\u75c7\u53ca\u8a98\u767c\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u3002\u900f\u904e\u4ecb\u5165\u9810\u9632\u65b9\u6848\u53ef\u6e1b\u4f4e\u5fc3\u81df\u75c5\u548c\u4e2d\u98a8\u7684\u767c\u751f\u7387\u548c\u6b7b\u4ea1\u7387\uff0c\u4f46\u6cbb\u7642\u6548\u679c\u5f80\u5f80\u9700\u8981\u5f88\u9577\u6642\u9593\uff0c\u4f8b\u598210\u81f320\u5e74\uff0c\u624d\u80fd\u986f\u73fe\u51fa\u4f86\uff0c\u7814\u7a76\u6210\u672c\u56e0\u800c\u5f88\u9ad8\uff1bIMT\u9019\u7a2e\u9810\u5f8c\u65e9\u671f\u6307\u6a19\u7684\u8b8a\u5316\uff0c\u5247\u53ef\u5728\u6578\u500b\u6708\u5167\u770b\u5230\u3002\u9019\u53cd\u6620\u900f\u904e\u91cf\u5ea6IMT\u4f5c\u70ba\u8a55\u4f30\u91dd\u5c0dPM2.5\u76f8\u95dc\u7684\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u9810\u9632\u8a08\u5283\uff0c\u662f\u4e00\u7a2e\u5be6\u969b\u53ef\u884c\u7684\u5275\u65b0\u65b9\u6cd5\u3002\u300d<\/p>\r\n<p><strong>\u91dd\u5c0d\u9ad8\u7a7a\u6c23\u6c61\u67d3\u7a0b\u5ea6\u7684\u4ecb\u5165\u9810\u9632\u65b9\u6848<\/strong><\/p>\r\n<p>\u70ba\u4e86\u61c9\u5c0d\u7a7a\u6c23\u6c61\u67d3\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u5e36\u4f86\u7684\u6311\u6230\uff0c\u4e2d\u5927\u91ab\u5b78\u9662\u7814\u7a76\u5718\u968a\u5c07\u958b\u5c55\u4e00\u9805\u96a8\u6a5f\u5b89\u6170\u5291\u5c0d\u7167\u5e72\u9810\u7814\u7a76\uff0c\u53c3\u52a0\u8005\uff08\u5c24\u5176\u662f\u66dd\u9732\u65bc\u9ad8\u7a7a\u6c23\u6c61\u67d3\u74b0\u5883\u7684\u8077\u696d\uff0c\u5982\u5df4\u58eb\u6216\u7684\u58eb\u53f8\u6a5f\u3001\u5eda\u5e2b\u6216\u5efa\u7bc9\u5730\u76e4\u5de5\u4eba\u7b49\uff09\u5c07\u88ab\u96a8\u6a5f\u5206\u914d\u670d\u7528\u80ba\u90e8\u6297\u708e\u85e5\uff08montelukast\uff09\u6216\u5b89\u6170\u5291\uff0c\u70ba\u671f\u534a\u5e74\uff0c\u5176\u5f8c\u6bd4\u8f03FMD\u53caIMT\u9019\u5169\u500b\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u66ff\u4ee3\u6307\u6a19\u7684\u8b8a\u5316\uff0c\u4ee5\u4e86\u89e3\u53ca\u65e9\u900f\u904e\u85e5\u7269\u9810\u9632\u9ad8\u5371\u4eba\u58eb\u56e0\u7a7a\u6c23\u6c61\u67d3\u5f15\u81f4\u8840\u7ba1\u786c\u5316\u7684\u529f\u6548\u3002<\/p>\r\n<p>\u8ca0\u8cac\u6709\u95dc\u7814\u7a76\u7684\u5fc3\u81df\u79d1\u5c08\u79d1\u91ab\u751f\u3001\u4e2d\u5927\u91ab\u5b78\u9662\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u5ba2\u5ea7\u6559\u6388<strong>\u80e1\u9326\u751f\u91ab\u751f<\/strong>\u88dc\u5145\uff1a\u300c\u6211\u5011\u7684\u7814\u7a76\u5c07\u9032\u4e00\u6b65\u5370\u8b49\u7a7a\u6c23\u6c61\u67d3\u8207\u8840\u7ba1\u75c5\u8b8a\u7684\u95dc\u4fc2\uff0c\u4e26\u70ba\u65e5\u5f8c\u4ecb\u5165\u9810\u9632\u8840\u7ba1\u75c5\u8b8a\uff0c\u63d0\u4f9b\u6709\u529b\u4f9d\u64da\uff0c\u5e0c\u671b\u900f\u904e\u5404\u754c\u52aa\u529b\u6539\u5584\u7a7a\u6c23\u6c61\u67d3\u554f\u984c\uff0c\u4ee5\u6e1b\u4f4e\u8840\u7ba1\u786c\u5316\u5c0d\u60a3\u8005\u9020\u6210\u7684\u5f71\u97ff\u548c\u91ab\u7642\u8ca0\u64d4\u3002\u300d<\/p>\r\n<p>\u7814\u7a76\u8207\u91cd\u6176\u91ab\u79d1\u5927\u5b78\u5408\u4f5c\u3002\u6709\u8208\u8da3\u53c3\u52a0\u8005\u8acb\u767b\u5165\u4ee5\u4e0b\u7db2\u5740\u586b\u5beb\u8868\u683c\u53ca\u905e\u4ea4\u767b\u8a18\uff1a<a href=\"https:\/\/bit.ly\/3a9rbDz\">https:\/\/bit.ly\/3a9rbDz<\/a>\u3002<\/p>\r\n<p>\u8a3b1\uff1aThe impact of particulate matter air pollution (PM2.5) on atherosclerosis in modernizing China: a report from the CATHAY study. <em>International Journal of Epidemiology (2020)<\/em><\/p>\r\n<p><a href=\"https:\/\/academic.oup.com\/ije\/advance-article\/doi\/10.1093\/ije\/dyaa235\/6012822?login=true\">https:\/\/academic.oup.com\/ije\/advance-article\/doi\/10.1093\/ije\/dyaa235\/6012822?login=true<\/a><\/p>\r\n<p>\u8a3b2\uff1a\u9818\u5148\u7684\u5fc3\u8840\u7ba1\u7d44\u7e54\u547c\u7c72\u63a1\u53d6\u7dca\u6025\u884c\u52d5\u4ee5\u6e1b\u5c11\u7a7a\u6c23\u6c61\u67d3<br \/>\r\n<a href=\"https:\/\/www.world-heart-federation.org\/news\/leading-cardiovascular-organizations-call-for-urgent-action-to-reduce-air-pollution\/\">https:\/\/www.world-heart-federation.org\/news\/leading-cardiovascular-organizations-call-for-urgent-action-to-reduce-air-pollution\/<\/a><\/p>\r\n<p>\u8a3b3\uff1aBots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. Common carotid intima-media thickness and risk of stroke and myocardial infarction: The Rotterdam Study. 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