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elegans\uff09\u7cbe\u5b50\u5185\u7684\u7ebf\u7c92\u4f53\uff0c\u5c1d\u8bd5\u627e\u51fa\u7b54\u6848\u3002\u79c0\u4e3d\u9690\u6746\u7ebf\u866b\u662f\u4e00\u79cd\u975e\u5bc4\u751f\u7ebf\u866b\uff0c\u53ef\u4ee5\u72ec\u7acb\u751f\u5b58\uff0c\u8eab\u957f\u7ea61\u6beb\u7c73\uff0c\u4e00\u822c\u751f\u957f\u4e8e\u6e29\u5e26\u6ce5\u571f\u4e2d\u3002\u79d1\u5b66\u5bb6\u957f\u4e45\u4ee5\u6765\u5229\u7528\u79c0\u4e3d\u9690\u6746\u7ebf\u866b\u4f5c\u7ec6\u80de\u7814\u7a76\uff0c\u662f\u751f\u7269\u5b66\u7814\u7a76\u7684\u4e00\u79cd\u6a21\u5f0f\u751f\u7269\uff08model organism\uff09\u3002\u79d1\u5b66\u5bb6\u5df2\u77e5\u9053\uff0c\u7ebf\u866b\u6bcd\u4eb2\u7684\u5375\u5b50\u7ec6\u80de\u4f1a\u4ea7\u751f\u81ea\u566c\u4f5c\u7528\uff0c\u541e\u566c\u7cbe\u5b50\u7684\u7ebf\u7c92\u4f53\uff0c\u5e76\u5c06\u5b83\u4eec\u5206\u89e3\uff08degradation\uff09\u3002\u4f46<strong>\u59dc\u6559\u6388\u53ca\u7814\u7a76\u56e2\u961f\u5229\u7528\u9ad8\u89e3\u6790\u5ea6\u7684\u7535\u5b50\u663e\u5fae\u955c\uff0c\u89c2\u5bdf\u7ebf\u866b\u7ec6\u80de\u5185\u90e8\u7ed3\u6784\u5c0f\u81f3\u7eb3\u7c73\u5c3a\u5ea6\u7684\u4e09\u7ef4\u5f71\u50cf<\/strong>\u65f6\uff0c\u53d1\u73b0\u7cbe\u5b50\u7ebf\u7c92\u4f53\u5728\u6bcd\u4eb2\u5375\u5b50\u7684\u81ea\u566c\u4f5c\u7528\u53d1\u751f\u4e4b\u524d\uff0c\u5df2\u7ecf\u51fa\u73b0\u8870\u9000\u7684\u8ff9\u8c61\u3002&nbsp;<\/p><p>\u59dc\u6559\u6388\u8868\u793a\uff1a\u300c<strong>\u6211\u4eec\u53d1\u73b0\u7cbe\u5b50\u7ebf\u7c92\u4f53\u6709\u81ea\u6211\u5206\u89e3\u7684\u673a\u5236\uff08<\/strong><strong>self-degradation<\/strong><strong>\uff09\uff0c\u5982\u540c\u4e00\u79cd\u81ea\u6740\u884c\u4e3a\u3002\u5f53\u7cbe\u5b50\u8fdb\u5165\u5375\u5b50\u65f6\uff0c\u8fd9\u4e2a\u5185\u5728\u673a\u5236\u5c31\u4f1a\u7acb\u5373\u542f\u52a8\u3002\u6211\u4eec\u66f4\u53d1\u73b0\u5f53\u6b64\u673a\u5236\u906d\u5230\u5ef6\u7f13\uff0c\u80da\u80ce\u7684\u751f\u5b58\u7387\u4fbf\u4f1a\u964d\u4f4e\u3002\u6b64\u53d1\u73b0\u6709\u52a9\u79d1\u5b66\u5bb6\u4e86\u89e3\u4e0e\u6b64\u673a\u5236\u76f8\u5173\u7684\u75be\u75c5\uff0c\u4ee5\u53ca\u6539\u5584\u4eba\u5de5\u6388\u5b55\u7684\u6280\u672f\u3002<\/strong>\u300d&nbsp;<\/p><p>\u57fa\u4e8e\u4ee5\u4e0a\u7684\u53d1\u73b0\uff0c\u7814\u7a76\u56e2\u961f\u518d\u8fdb\u4e00\u6b65\u5bfb\u627e\u4fc3\u8fdb\u7cbe\u5b50\u7ebf\u7c92\u4f53\u81ea\u6211\u5206\u89e3\u7684\u86cb\u767d\u8d28\uff0c\u53d1\u73b0\u4e8e\u7ebf\u7c92\u4f53\u8868\u9762\u7684CPS-6\u86cb\u767d\u6709\u5207\u65adDNA\u5206\u5b50\u7684\u529f\u80fd\u3002\u6b64\u53d1\u73b0\u5728\u5206\u5b50\u5c42\u9762\u76f4\u63a5\u89e3\u91ca\u4e86\u4e3a\u4f55\u7ebf\u7c92\u4f53DNA\u4e0d\u80fd\u901a\u8fc7\u7236\u7cfb\u9057\u4f20\uff1a\u5f53\u7cbe\u5b50\u8fdb\u5165\u5375\u5b50\u65f6\uff0cCPS-6\u86cb\u767d\u4f1a\u79fb\u52a8\u5230\u7cbe\u5b50\u7ebf\u7c92\u4f53\u4e0a\u5e76\u5206\u89e3\u5176DNA\u3002\u7814\u7a76\u4eba\u5458\u66f4\u53d1\u73b0\uff0c\u5047\u5982\u7236\u4eb2\u7684\u7ebf\u7c92\u4f53\u4e0d\u88ab\u6e05\u9664\uff0c\u5c06\u4f1a\u4f24\u5bb3\u53d1\u80b2\u4e2d\u7684\u80da\u80ce\u3002&nbsp;<\/p><p>\u7531\u4e8e\u7ebf\u7c92\u4f53\u4e3a\u7ec6\u80de\u4ee3\u8c22\u63d0\u4f9b\u80fd\u91cf\u65f6\uff0c\u975e\u5e38\u5bb9\u6613\u53d7\u5230\u635f\u4f24\uff0c\u56e0\u6b64\u5b83\u4eec\u53d7\u5230\u7ec6\u80de\u81ea\u566c\u7cfb\u7edf\u7684\u4e25\u5bc6\u76d1\u5bdf\uff0c\u5f02\u5e38\u7684\u7ebf\u7c92\u4f53\u4f1a\u88ab\u81ea\u566c\u4f5c\u7528\u6e05\u9664\u3002\u5728\u4eba\u4f53\u4e2d\uff0c\u5982\u679c\u8fd9\u4e2a\u6e05\u9664\u529f\u80fd\u53d1\u751f\u5f02\u5e38\uff0c\u4fbf\u6709\u53ef\u80fd\u5f15\u81f4\u795e\u7ecf\u9000\u5316\u75be\u75c5\u3002<strong>\u6df1\u5165\u4e86\u89e3\u7ebf\u866b\u7684\u7236\u7cfb\u7ebf\u7c92\u4f53<\/strong><strong>DNA<\/strong><strong>\u7684\u6e05\u9664\u8fc7\u7a0b\uff0c\u5c06\u4e3a\u7814\u7a76\u4eba\u4f53\u7ec6\u80de\u7684\u81ea\u566c\u7cfb\u7edf\u63d0\u4f9b\u65b0\u65b9\u5411\uff0c\u751a\u81f3\u53ef\u4e3a\u76f8\u5173\u7684\u75be\u75c5\u63d0\u4f9b\u6cbb\u7597\u65b9\u6cd5\uff0c\u5305\u62ec\u5e15\u91d1\u900a\u75c7\u3001\u8111\u9000\u5316\u75c7\u3001\u4e00\u4e9b\u5fc3\u810f\u75be\u75c5\u53ca\u5931\u660e\u7b49\u3002<\/strong>&nbsp;<\/p><p>\u59dc\u6559\u6388\u7eed\u8bf4\uff1a\u300c<strong>\u591a\u5b66\u79d1\u7814\u7a76\u65b9\u6cd5\u5bf9\u4e8e\u89e3\u7b54\u751f\u7269\u5b66\u4e2d\u7684\u96be\u9898\u975e\u5e38\u91cd\u8981\u3002\u662f\u6b21\u7814\u7a76\u7ed3\u5408\u4e86\u5148\u8fdb\u7535\u5b50\u663e\u5fae\u955c\u6210\u50cf\u6280\u672f\u548c\u751f\u7269\u5316\u5b66\u6280\u672f\uff08\u641c\u5bfb\u86cb\u767d\uff09\uff0c\u7f3a\u4e00\u4e0d\u53ef\u3002\u662f\u6b21\u7814\u7a76\u7684\u6210\u529f\uff0c\u5c55\u73b0\u4e86\u62e5\u6709\u4e0d\u540c\u4e13\u957f\u6280\u672f\u7684\u5b9e\u9a8c\u5ba4\u7d27\u5bc6\u5408\u4f5c\u7684\u91cd\u8981\u6027\u3002<\/strong>\u6211\u5728\u6b64\u8877\u5fc3\u611f\u8c22\u9999\u6e2f\u7814\u7a76\u8d44\u52a9\u5c40\u7684\u5353\u8d8a\u5b66\u79d1\u9886\u57df\u8ba1\u5212\u5bf9\u4e2d\u5927\u7ec6\u80de\u5668\u751f\u7269\u5408\u6210\u548c\u529f\u80fd\u7814\u7a76\u4e2d\u5fc3\u7684\u652f\u6301\uff0c\u8ba9\u6211\u4eec\u53ef\u4ee5\u8fd0\u7528\u5148\u8fdb\u7684\u7535\u5b50\u663e\u5fae\u955c\u6280\u672f\u4e8e\u662f\u6b21\u7814\u7a76\u4e2d\u3002\u300d&nbsp;<\/p><p><strong>\u59dc\u79c9\u660a\u6559\u6388\u7b80\u5386<\/strong>&nbsp;<\/p><p>\u59dc\u79c9\u660a\u6559\u6388\u73b0\u4efb\u751f\u547d\u79d1\u5b66\u5b66\u9662\u526f\u6559\u6388\uff0c\u540c\u65f6\u4e5f\u662f\u4e2d\u5927\u7ec6\u80de\u5668\u751f\u7269\u5408\u6210\u548c\u529f\u80fd\u7814\u7a76\u4e2d\u5fc3\u7684\u6210\u5458\uff0c\u7814\u7a76\u4e2d\u5fc3\u83b7\u9999\u6e2f\u7814\u7a76\u8d44\u52a9\u5c40\u5353\u8d8a\u5b66\u79d1\u9886\u57df\u8ba1\u5212\u8d44\u52a9\uff08AoE\/M-05\/12\uff09\u3002\u59dc\u6559\u6388\u5728\u9996\u5c14\u5927\u5b66\u53d6\u5f97\u5316\u5b66\u5b66\u58eb\u5b66\u4f4d\uff0c\u5e76\u5728\u5a01\u65af\u5eb7\u8f9b\u5927\u5b66\u9ea6\u8fea\u900a\u5206\u6821\u83b7\u5f97\u751f\u7269\u5316\u5b66\u535a\u58eb\u5b66\u4f4d\u3002\u5728\u52a0\u5165\u4e2d\u5927\u4e4b\u524d\uff0c\u4ed6\u5728\u4f5b\u7f57\u91cc\u8fbe\u5927\u5b66\u5fae\u751f\u7269\u4e0e\u7ec6\u80de\u751f\u7269\u5b66\u7cfb\u4efb\u526f\u6559\u6388\u3002&nbsp;<\/p><p>\u59dc\u6559\u6388\u662f\u7ec6\u80de\u751f\u7269\u5b66\u548c\u7535\u5b50\u663e\u5fae\u955c\u65b9\u9762\u7684\u4e13\u5bb6\u3002\u4ed6\u548c\u7814\u7a76\u56e2\u961f\u4f7f\u7528\u5206\u5b50\u751f\u7269\u5b66\u6280\u672f\u548c\u9ad8\u5206\u8fa8\u4e09\u7ef4\u7535\u5b50\u663e\u5fae\u955c\u6280\u672f\u7814\u7a76\u52a8\u690d\u7269\u7ec6\u80de\u5668\u751f\u7269\u5408\u6210\u3002\u4ed6\u5728\u7ebf\u866b\u7ec6\u80de\u51cb\u4ea1\u548c\u81ea\u566c\u65b9\u9762\u7684\u7814\u7a76\u53d6\u5f97\u4e86\u91cd\u8981\u7684\u6210\u679c\uff0c\u5176\u7814\u7a76\u6210\u679c\u5728\u4f17\u591a\u77e5\u540d\u56fd\u9645\u79d1\u5b66\u671f\u520a\u4e0a\u53d1\u8868\uff0c\u5305\u62ec<em>Science, Molecular Cell, Current Biology, Proceedings National Academy Sciences of USA, Plant Cell, and Plant Physiology<\/em>\u3002&nbsp;<\/p><p>\u4e2d\u5927\u7ec6\u80de\u5668\u751f\u7269\u5408\u6210\u548c\u529f\u80fd\u7814\u7a76\u4e2d\u5fc3\u7f51\u9875\uff1a<a href=\"http:\/\/www.cuhk.edu.hk\/centre\/iCell\/\">http:\/\/www.cuhk.edu.hk\/centre\/iCell\/<\/a>&nbsp;<\/p><p>* \u300a\u79d1\u5b66\u300b\u6742\u5fd7\u539f\u6587: Mitochondrial endonuclease G mediated breakdown of paternal mitochondria upon fertilization. Science <a href=\"http:\/\/dx.doi.org\/10.1126\/science.aaf4777\">http:\/\/dx.doi.org\/10.1126\/science.aaf4777<\/a> (2016)<\/p>","show_as_achievement":false,"achievement_category":[],"show_as_clarification":false,"show_as_announcement":false,"photos":null,"attachments":null,"video_source":null,"video_file":null,"add_play_button":false,"video_caption":"","show_migration":false,"original_id":"2311","photos_original":[{"photo":"5796dd5cb12d6.jpg","caption":"\u59dc\u79c9\u660a\u6559\u6388\u5229\u7528\u9ad8\u89e3\u6790\u5ea6\u7535\u5b50\u663e\u5fae\u955c\u7814\u7a76\u7ebf\u866b\uff0c\u63ed\u793a\u7cbe\u5b50\u7ebf\u7c92\u4f53\u7684\u81ea\u6211\u5206\u89e3\u673a\u5236\uff0c\u6210\u679c\u520a\u4e8e\u300a\u79d1\u5b66\u300b\u671f\u520a"},{"photo":"5796dd5e0ca28.jpg","caption":"\u59dc\u79c9\u660a\u6559\u6388\u53ca\u5176\u7814\u7a76\u56e2\u961f"},{"photo":"5796dd60e1272.jpg","caption":"\u5375\u6bcd\u7ec6\u80de\u4ea7\u751f\u81ea\u566c\u4f5c\u7528\uff08\u7ea2\uff09\u541e\u566c\u7cbe\u5b50\u7ebf\u7c92\u4f53\uff08\u84dd\uff09\u7684\u4e09\u7ef4\u56fe\u50cf\u3002\u56fe\u50cf\u4e43\u6839\u636e\u7535\u5b50\u663e\u5fae\u955c\u6570\u636e\u5236\u6210\u3002"},{"photo":"5796dd611e867.jpg","caption":"\u79c0\u4e3d\u9690\u6746\u7ebf\u866b\uff08\u6210\u866b\uff0c\u8eab\u957f1mm\uff09\u53ca\u5176\u5375\u5b50"},{"photo":"5796dd6140cdb.jpg","caption":"\u7535\u5b50\u663e\u5fae\u955c\u4e0b\u5728\u7ebf\u866b\u80da\u80ce\u91cc\u7684\u7ebf\u7c92\u4f53"}],"attachments_original":null},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/press\/49291","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/press"}],"about":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/types\/press"}],"version-history":[{"count":0,"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/press\/49291\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/media?parent=49291"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/tags?post=49291"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}