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1992\uff09\u3001\u53d1\u73b0\u4ece\u9644\u777e\u5934\u90e8\u5206\u6ccc\u7684\u4e00\u4e2a\u65b0\u9632\u5fa1\u7d20\u53ca\u5176\u5bf9\u7cbe\u5b50\u6210\u719f\u7684\u5f71\u54cd\uff08\u300a\u79d1\u5b66\u6742\u5fd7\u300b<em>Science<\/em>, 2001\u53ca\u300a\u81ea\u7136\u2014\u7ec6\u80de\u751f\u7269\u5b66\u300b<em>Nature Cell Biology<\/em>, 2004\uff09\u53ca\u56ca\u6027\u7ea4\u7ef4\u5316\u8de8\u819c\u7535\u5bfc\u8c03\u8282\u5668\uff08CFTR\uff09\u5728\u751f\u6b96\u53ca\u4e0d\u80b2\u4e2d\u7684\u89d2\u8272\uff08\u300a\u81ea\u7136\u2014\u7ec6\u80de\u751f\u7269\u5b66\u300b<em>Nature Cell Biology<\/em>, 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Y. 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