{"id":146551,"date":"2023-06-08T10:45:12","date_gmt":"2023-06-08T02:45:12","guid":{"rendered":"https:\/\/www.cpr.cuhk.edu.hk\/?post_type=press&p=146551"},"modified":"2023-06-08T11:04:07","modified_gmt":"2023-06-08T03:04:07","slug":"cuhk-identifies-a-new-genetic-marker-to-predict-heart-disease-risk-in-people-with-diabetes-study-finding-highlights-the-potential-of-precision-medicine-in-diabetes","status":"publish","type":"press","link":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/press\/cuhk-identifies-a-new-genetic-marker-to-predict-heart-disease-risk-in-people-with-diabetes-study-finding-highlights-the-potential-of-precision-medicine-in-diabetes\/","title":{"rendered":"\u4e2d\u5927\u767c\u73fe\u65b0\u57fa\u56e0\u6a19\u8a18\u53ef\u9810\u6e2c\u7cd6\u5c3f\u75c5\u4eba\u60a3\u51a0\u5fc3\u75c5\u98a8\u96aa \u51f8\u986f\u7cd6\u5c3f\u75c5\u7cbe\u6e96\u6cbb\u7642\u7684\u6f5b\u529b"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","tags":[],"class_list":["post-146551","press","type-press","status-publish","hentry"],"acf":{"title_alt":"","sub_title_alt":"","press_date":"20230608","keep":false,"details":"

\u9999\u6e2f\u4e2d\u6587\u5927\u5b78\uff08\u4e2d\u5927\uff09\u91ab\u5b78\u9662\u7814\u7a76\u5718\u968a\u767c\u73fe\u4e00\u500b\u53ef\u9810\u6e2c\u7cd6\u5c3f\u75c5\u4eba\u60a3\u51a0\u5fc3\u75c5\u98a8\u96aa\u7684\u57fa\u56e0\u6a19\u8a18\uff0c\u5c07\u6709\u52a9\u63a8\u9032\u7cd6\u5c3f\u75c5\u7684\u500b\u4eba\u5316\u6cbb\u7642\u3002\u7814\u7a76\u8a73\u60c5\u525b\u65bc\u672c\u6708\u5728\u7cd6\u5c3f\u79d1\u6b0a\u5a01\u671f\u520a\u300aDiabetes Care\u300b\u767c\u8868\u3002<\/p>\r\n

\u7cd6\u5c3f\u75c5\u4eba\u60a3\u51a0\u5fc3\u75c5\u98a8\u96aa\u9ad8<\/strong>2<\/strong>\u81f3<\/strong>3<\/strong>\u500d<\/strong><\/p>\r\n

\u6839\u64da\u885e\u751f\u7f722020\u81f32022\u5e74\u4eba\u53e3\u5065\u5eb7\u8abf\u67e5\u5831\u544a\uff0c\u672c\u6e2f15\u6b72\u6216\u4ee5\u4e0a\u4eba\u58eb\u7576\u4e2d\uff0c\u67098.5%\u60a3\u6709\u7cd6\u5c3f\u75c5\u3002\u6587\u737b\u6307\u51fa\u7cd6\u5c3f\u75c5\u4eba\u60a3\u4e0a\u51a0\u5fc3\u75c5\u7684\u98a8\u96aa\u8f03\u975e\u7cd6\u5c3f\u75c5\u4eba\u9ad82\u81f33\u500d\u3002<\/p>\r\n

\u4e2d\u5927\u91ab\u5b78\u9662\u4f55\u5584\u8861\u7cd6\u5c3f\u79d1\u6559\u6388\u3001\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u5167\u5206\u6ccc\u53ca\u7cd6\u5c3f\u79d1\u4e3b\u4efb\uff08\u5b78\u8853\uff09\u517c\u9999\u6e2f\u7cd6\u5c3f\u75c5\u751f\u7269\u5eab\u9996\u5e2d\u7814\u7a76\u54e1\u99ac\u9752\u96f2\u6559\u6388<\/strong>\u6307\u51fa\uff1a\u300c\u51a0\u5fc3\u75c5\u662f\u5c0e\u81f4\u7cd6\u5c3f\u75c5\u4eba\u5165\u9662\u6216\u8eab\u9ad4\u6b20\u4f73\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u800c\u7cd6\u5c3f\u75c5\u662f\u5f15\u767c\u51a0\u5fc3\u75c5\u7684\u7368\u7acb\u98a8\u96aa\u56e0\u7d20\u3002\u6211\u5011\u6b64\u7814\u7a76\u6210\u529f\u767c\u73fe\u4e00\u500b\u65b0\u57fa\u56e0\u6a19\u8a18\uff0c\u53ef\u6709\u52a9\u627e\u51fa\u5177\u9ad8\u51a0\u5fc3\u75c5\u98a8\u96aa\u7684\u7cd6\u5c3f\u75c5\u60a3\u8005\uff0c\u5236\u8a02\u500b\u4eba\u5316\u6cbb\u7642\u65b9\u6848\uff0c\u70ba\u7cd6\u5c3f\u75c5\u7cbe\u6e96\u6cbb\u7642\u5960\u4e0b\u6839\u57fa\u3002\u300d<\/p>\r\n

\u65b0\u57fa\u56e0\u6a19\u8a18\u8207\u8840\u58d3\u53ca\u5fc3\u81df\u75c5\u76f8\u95dc<\/strong><\/p>\r\n

\u4e2d\u5927\u91ab\u5b78\u9662\u7814\u7a76\u5718\u968a\u5229\u75283,596\u500b\u60a3\u6709\u51a0\u5fc3\u75c5\u7684\u7cd6\u5c3f\u75c5\u4eba\u3001\u8d85\u904e6\u767e\u842c\u500b\u57fa\u56e0\u8b8a\u7570\uff0c\u82078,898\u500b\u6c92\u6709\u51a0\u5fc3\u75c5\u7684\u672c\u5730\u7cd6\u5c3f\u75c5\u60a3\u8005\u9032\u884c\u57fa\u56e0\u5c0d\u6bd4\uff0c\u5c07\u5f97\u51fa\u6578\u64da\u8207\u5168\u7403\u903e50\u842c\u4eba\u7684\u57fa\u56e0\u8cc7\u6599\u518d\u4f5c\u5206\u6790\uff0c\u6210\u529f\u767c\u73fe\u4e00\u500b\u540d\u70ba\u300cPDE1A<\/em> rs10171703\u300d\u7684\u65b0\u57fa\u56e0\u6a19\u8a18\uff0c\u53ef\u7528\u4ee5\u9810\u6e2c\u83ef\u4eba\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u5fc3\u81df\u75c5\u98a8\u96aa\u3002\u7d50\u679c\u986f\u793a\uff0c\u651c\u5e36\u6b64\u57fa\u56e0\u6a19\u8a18\u7684\u4e8c\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u51fa\u73fe\u5fc3\u81df\u75c5\u6216\u5fc3\u8166\u8840\u7ba1\u75be\u75c5\u7684\u6a5f\u6703\u7387\u8f03\u6c92\u6709\u6b64\u57fa\u56e0\u6a19\u8a18\u7684\u4e8c\u578b\u60a3\u8005\u9ad8\u7d0420%\u3002<\/p>\r\n

\u4e2d\u5927\u91ab\u5b78\u9662\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u5167\u5206\u6ccc\u53ca\u7cd6\u5c3f\u79d1\u526f\u7814\u7a76\u54e1\u8b5a\u590f\u4ead<\/strong>\u535a\u58eb<\/strong>\u8868\u793a\uff1a\u300c\u6211\u5011\u7e7c\u800c\u767c\u73fePDE1A<\/em> rs10171703\u8207\u8840\u58d3\u4e0a\u5347\u76f8\u95dc\u3002\u7531\u65bc\u8840\u58d3\u9ad8\u8207\u5fc3\u81df\u75c5\u98a8\u96aa\u6709\u5bc6\u5207\u95dc\u806f\uff0c\u6216\u8a31\u4ea6\u53ef\u89e3\u91cb\u70ba\u4f55\u651c\u5e36\u6b64\u57fa\u56e0\u6a19\u8a18\u7684\u7cd6\u5c3f\u75c5\u60a3\u8005\u6709\u8f03\u9ad8\u5fc3\u81df\u75c5\u98a8\u96aa\u3002\u300d<\/p>\r\n

\u4e2d\u5927\u91ab\u5b78\u9662\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u8b1b\u5ea7\u6559\u6388\u517c\u9999\u6e2f\u7cd6\u5c3f\u75c5\u53ca\u80a5\u80d6\u75c7\u7814\u7a76\u6240\u6240\u9577\u9673\u91cd\u5a25\u6559\u6388<\/strong>\u6307\u51fa\uff1a\u300c\u651c\u5e36\u6b64\u57fa\u56e0\u6a19\u8a18\u7684\u7cd6\u5c3f\u75c5\u4eba\u5982\u679c\u80fd\u5920\u59a5\u5584\u7ba1\u7406\u8840\u58d3\u81f3\u7406\u60f3\u6c34\u5e73\uff0c\u5176\u60a3\u4e0a\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u98a8\u96aa\u53ef\u5927\u6e1b40%\u3002\u900f\u904e\u4f7f\u7528\u57fa\u56e0\u6a19\u8a18\uff0c\u6211\u5011\u80fd\u5920\u8fa8\u8a8d\u51fa\u5177\u8f03\u9ad8\u5fc3\u81df\u75c5\u98a8\u96aa\u7684\u7cd6\u5c3f\u75c5\u4eba\uff0c\u5f9e\u800c\u7763\u4fc3\u4ed6\u5011\u6539\u5584\u8840\u58d3\u53ca\u5176\u4ed6\u98a8\u96aa\u56e0\u7d20\uff0c\u6e1b\u4f4e\u51fa\u73fe\u5fc3\u81df\u75c5\u7684\u6a5f\u6703\u3002\u300d<\/p>\r\n

\u4e2d\u5927\u91ab\u5b78\u9662\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u5167\u5206\u6ccc\u53ca\u7cd6\u5c3f\u79d1\u79d1\u5b78\u4e3b\u4efb\u6797\u61ac\u6ce2\u535a\u58eb<\/strong>\u8868\u793a\uff1a\u300c\u7cbe\u6e96\u91ab\u7642\u6108\u8da8\u6d41\u884c\uff0c\u800c\u6211\u5011\u7684\u7814\u7a76\u7d50\u679c\u5145\u5206\u986f\u793a\u57fa\u56e0\u907a\u50b3\u5c0d\u65bc\u500b\u4eba\u7684\u5fc3\u81df\u75c5\u98a8\u96aa\u6709\u91cd\u8981\u7684\u5f71\u97ff\u3002\u300d<\/p>\r\n

\u99ac\u9752\u96f2\u6559\u6388<\/strong>\u88dc\u5145\uff1a\u300c\u6211\u5011\u7684\u7814\u7a76\u51f8\u986f\u57fa\u56e0\u7d44\u91ab\u5b78\u7684\u6f5b\u529b\uff0c\u5229\u7528\u57fa\u56e0\u4fe1\u606f\u5f15\u9818\u672a\u4f86\u7684\u6cbb\u7642\u65b9\u5411\u3002\u80fd\u5920\u6210\u529f\u5b8c\u6210\u6b64\u5927\u578b\u7814\u7a76\uff0c\u6211\u5011\u8877\u5fc3\u611f\u8b1d\u5404\u500b\u8cc7\u52a9\u6a5f\u69cb\uff0c\u7279\u5225\u662f\u9999\u6e2f\u7814\u7a76\u8cc7\u52a9\u5c40\u4e3b\u984c\u7814\u7a76\u8a08\u5283\u548c\u7814\u7a76\u5f71\u97ff\u57fa\u91d1\u3002\u53e6\u5916\uff0c\u6211\u5011\u4ea6\u8981\u611f\u8b1d\u53c3\u8207\u7814\u7a76\u7684\u5404\u4f4d\u7cd6\u5c3f\u75c5\u60a3\u8005\u3002\u300d<\/p>\r\n

\u662f\u9805\u7814\u7a76\u7372\u9999\u6e2f\u7814\u7a76\u8cc7\u52a9\u5c40\u4e3b\u984c\u7814\u7a76\u8a08\u5283\u548c\u7814\u7a76\u5f71\u97ff\u57fa\u91d1\u8cc7\u52a9\uff0c\u53ca\u591a\u500b\u7d44\u7e54\u8cc7\u52a9\u7814\u7a76\u3002<\/p>\r\n

\u7814\u7a76\u8ad6\u6587\u53ef\u53c3\u95b1\uff1ahttps:\/\/doi.org\/10.2337\/dc22-2331<\/a><\/p>","show_as_achievement":false,"achievement_category":[],"show_as_clarification":false,"show_as_announcement":false,"photos":[{"photo":146554,"caption":"\u4e2d\u5927\u91ab\u5b78\u9662\u767c\u73fe\u4e00\u500b\u53ef\u9810\u6e2c\u7cd6\u5c3f\u75c5\u4eba\u60a3\u51a0\u5fc3\u75c5\u98a8\u96aa\u7684\u57fa\u56e0\u6a19\u8a18\u300cPDE1A rs10171703\u300d\u3002\u651c\u5e36\u6b64\u57fa\u56e0\u6a19\u8a18\u7684\u4e8c\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\uff0c\u51fa\u73fe\u5fc3\u81df\u75c5\u6216\u5fc3\u8166\u8840\u7ba1\u75be\u75c5\u7684\u6a5f\u6703\u7387\u8f03\u6c92\u6709\u6b64\u57fa\u56e0\u6a19\u8a18\u7684\u4e8c\u578b\u60a3\u8005\u9ad8\u7d0420%\u3002\u7814\u7a76\u767c\u73fe\u5c07\u6709\u52a9\u63a8\u9032\u7cd6\u5c3f\u75c5\u7684\u500b\u4eba\u5316\u6cbb\u7642\u3002\r\n\uff08\u5de6\u8d77\uff09\u4e2d\u5927\u91ab\u5b78\u9662\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u540d\u8b7d\u81e8\u5e8a\u526f\u6559\u6388\u8607\u8a60\u5100\u91ab\u751f\u3001\u4e2d\u5927\u91ab\u5b78\u9662\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u8b1b\u5ea7\u6559\u6388\u9673\u91cd\u5a25\u6559\u6388\u3001\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u5167\u5206\u6ccc\u53ca\u7cd6\u5c3f\u79d1\u526f\u7814\u7a76\u54e1\u8b5a\u590f\u4ead\u535a\u58eb\u3001\u4e2d\u5927\u4f55\u5584\u8861\u7cd6\u5c3f\u79d1\u6559\u6388\u99ac\u9752\u96f2\u6559\u6388\u3001\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u5167\u5206\u6ccc\u53ca\u7cd6\u5c3f\u79d1\u79d1\u5b78\u4e3b\u4efb\u6797\u61ac\u6ce2\u535a\u58eb\u53ca\u5167\u79d1\u53ca\u85e5\u7269\u6cbb\u7642\u5b78\u7cfb\u6559\u6388\u9678\u5b89\u6b23\u6559\u6388\u3002"}],"attachments":null,"video_source":"","video_file":"","add_play_button":false,"video_caption":"","show_migration":false,"original_id":0,"photos_original":null,"attachments_original":null},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/press\/146551","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/press"}],"about":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/types\/press"}],"version-history":[{"count":4,"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/press\/146551\/revisions"}],"predecessor-version":[{"id":146558,"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/press\/146551\/revisions\/146558"}],"wp:attachment":[{"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/media?parent=146551"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cpr.cuhk.edu.hk\/sc\/wp-json\/wp\/v2\/tags?post=146551"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}